polyserositis (concato’s disease) due to granulocyte colony stimulating factor therapy for lymphoma
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Splenomegaly due to the use of granulocyte-colony stimulating factor.
Granulocyte-colony stimulating factor (G-CSF) is a growth factor used for stem-cell mobilization and neutropenia treatment. We report that splenomegaly was detected in a 16-years-old patient with acute lymphoblastic leukemia following the administration of G-CSF. The presence of splenomegaly in the patients receiving G-CSF may be related to the use of G-CSF.
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In the background section of their abstract, Woei-Cherng Shyu and associates state that because granulocyte colony-stimulating factor (G-CSF) has anti-inflammatory and neuroprotective properties and the capacity to mobilize stem cells, it has the potential to be used in treatment of stroke. However, there are limited data about the effects of G-CSF on hemostasis. It has been suggested that G-CS...
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Experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis, can be induced by immunization with a number of myelin antigens. In particular, myelin oligodendrocyte glycoprotein, a central nervous system (CNS)-specific antigen expressed on the myelin surface, is able to induce a paralytic MS-like disease with extensive CNS inflammation and demyelination in several strains of ...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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